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Selective Loss of Codon 72 Proline p53 and Frequent Mutational Inactivation of the Retained Arginine Allele in Colorectal Cancer

โœ Scribed by Schneider-Stock, Regine; Boltze, Carsten; Peters, Brigitte; Szibor, Reinhard; Landt, Olfert; Meyer, Frank; Roessner, Albert


Book ID
122316418
Publisher
Neoplasia Press
Year
2004
Tongue
English
Weight
168 KB
Volume
6
Category
Article
ISSN
1522-8002

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## BACKGROUND. Epidemiologic and genetic studies suggest that cancer of the right and left sides of the bowel arise through different mechanisms. To investigate the molecular mechanisms, allelic loss of chromosome 17p, p53 mutations, and microsatellite instability were analyzed in colorectal cance