## Abstract Protein farnesyltransferase (PFTase) catalyzes the attachment of a geranyl azide moiety to a peptide substrate, NโdansylโGlyโCysโValโIleโAlaโOH. The resulting azideโcontaining peptide was derivatized with a triphenylphosphineโbased reagent to generate an Oโalkyl imidateโlinked product,
Selective Labeling of Proteins by Using Protein Farnesyltransferase
โ Scribed by Benjamin P. Duckworth; Zhiyuan Zhang; Ayako Hosokawa; Mark D. Distefano
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 280 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1439-4227
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