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Selective involvement of BH3-only proteins and differential targets of Noxa in diverse apoptotic pathways

โœ Scribed by Zhang, L; Lopez, H; George, N M; Liu, X; Pang, X; Luo, X


Book ID
109842374
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
772 KB
Volume
18
Category
Article
ISSN
1350-9047

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## Abstract Apoptosis, a cell death mechanism regulated by Bclโ€2 family members, has been proposed as one of the mechanisms leading to neuronal loss in Huntington's disease (HD). Here we examined the regulation of Bclโ€2 family proteins in three different mouse models of HD with exon 1 mutant huntin