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Selective inhibitors of plasma kallikrein

✍ Scribed by D Michael Evans; D Michael Jones; Gary R Pitt; Javier Sueiras-Diaz; John Horton; Doreen Ashworth; Hoakan Olsson; Michael Szelke

Book ID
103571630
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
125 KB
Volume
32
Category
Article
ISSN
0162-3109

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During the course of the development of active center-directed plasmin inhibitors, it was found that N-(trans-4-aminomethylcyclohexanecarbonyl)-lysine-4-methoxycarbonylanilide inhibited plasma kallikrein more potently than other enzymes such as plasmin, urokinase, and thrombin, although the inhibito