Selective inhibition of transition from sexual agglutination to zygote formation by ethyl N-phenylcarbamate inSaccharomyces cerevisiae
✍ Scribed by Satoshi Hasegawa; Naohiko Yanagishima
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 629 KB
- Volume
- 137
- Category
- Article
- ISSN
- 0302-8933
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✦ Synopsis
Effects of ethyl N-phenylcarbamate (EPC) on the mating reaction of Saccharomyees cerevisiae were studied, with special attention on the effect on the c~ pheromone action. EPC inhibited zygote formation at a concentration which promoted induction of sexual agglutinability. EPC enhanced agglutinability induction by ~ pheromone, but inhibited e-pheromone-induced formation of large pearshaped cells in a mating type. The enhancement of agglutinability induction was accompanied with increased production of a agglutination substance and inhibition of c~ pheromone inactivation. EPC arrested the cell cycle of a cells probably in the step controlled by CDCI 9, CDC35, cAMPetc., just before the step controlled by CDC28, ~ pheromone etc.