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Selective inhibition of the lipoxygenase metabolic pathway of arachidonic acid by the SRS-A antagonist, FPL 55712

โœ Scribed by F.B. Casey; B.J. Appleby; D.C. Buck


Book ID
119049567
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
600 KB
Volume
25
Category
Article
ISSN
0090-6980

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Effect of dihomogammalinolenic acid and
โœ L. Iversen; K. Fogh; K. Kragballe ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 478 KB

The purpose of the present study was to determine the effect of the n-6 fatty acid, dihomogammalinolenic acid (DGLA, 20 : 3, n-6) on arachidonic acid (AA) (C20:4) metabolism by human peripheral mononuclear leukocytes (HPML). After incubation of HPML with A23187 (5 ~tM) and DGLA, the cyclooxygenase (