Differential inhibition of catecholamine
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Tae-Ju Park; So-Young Shin; Byung-Chang Suh; Eun-Kyung Suh; Ihn-Soon Lee; Yong-S
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Article
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1998
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John Wiley and Sons
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English
β 130 KB
π 2 views
We investigated the effects of amitriptyline, a tricyclic antidepressant, on [3H]norepinephrine ([3H]NE) secretion and ion flux in bovine adrenal chromaffin cells. Amitriptyline inhibited [3H]NE secretion induced by 1,1-dimethyl-4-phenylpiperazinium iodide (DMPP) and 70 mM K+. The half maximal inhib