Selective inhibition by 4,α-dimethyl-m-tyramine (H77/77) and 4-methyl-α-ethyl-m-tyramine (H75/12) of the monoamine oxidase within serotonergic and noradrenergic neurons in the rat brain

Inhibition of 4,α-dimethyl-m-tyramine (H

Inhibition of 4,α-dimethyl-m-tyramine (H 77/77)-induced hypermotil ity in rats by single and repeated administration of chlorpromazine, haloperidol, clozapine and thioridazine

✍ J. Buus Lassen 📂 Article 📅 1975 🏛 Springer 🌐 English ⚖ 486 KB

The effect of H 77/77 (5 mg/kg s.c.) on motility of rats kept in a familiar cage was investigated. H 77/77 produced hypermotility, which was reduced by oral pretreatment with chlorpromazine, haloperidol, clozapine and thioridazine. The 4 neuroleptics were administered acutely and for a 14 day period