Selective induction of T-cell subsets by antibodies to the T-cell antigen receptor and to the subset-specific differentiation antigens CD8 and CD4
β Scribed by Klaus Eichmann; Frank Emmrich
- Book ID
- 119528917
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 378 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0264-410X
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Nonpolymorphic interactions between the T cell differentiation antigens CD4 or CD8 and major histocompatibility complex (MHC)-encoded molecules have been postulated to participate in antigen recognition of MHC-restricted T cells. This would imply simultaneous binding of CD418 and of the T cell recep
We evaluated phenotype and apoptotic status of normal CD4 Ψ CD69 Ψ and CD8 Ψ CD69 Ψ peripheral blood T-lymphocytes after short-term challenge with escalating concentrations of phytohemagglutinin (PHA). The frequency of CD69-coexpressing CD4 Ψ and CD8 Ψ T-cells and CD69 staining intensity increased f