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Selective induction of NK cell proliferation and cytotoxicity by activated NKT cells

✍ Scribed by Gérard Eberl; H. Robson MacDonald


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
169 KB
Volume
30
Category
Article
ISSN
0014-2980

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High-level expression of cyclooxygenase (COX)-2 is reported in 80 -90% of colorectal adenocarcinomas. Selective inhibition of COX-2 was shown to reduce colorectal tumorigenesis in different models of carcinogenesis and to prevent metastasis in xenograft tumor models, as well as to suppress in vitro