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Selective induction of DNA synthesis in T and B lymphocytes

✍ Scribed by Jan Andersson; Göran Möller; Olof Sjöberg


Book ID
115810118
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
788 KB
Volume
4
Category
Article
ISSN
0008-8749

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The effect of sodium orthovanadate on enhancement of DNA synthesis by T and B cell mitogenic agents was studied using murine thymocytes and splenocytes. Addition of vanadate to thymocyte cultures inhibited the mitogenic response induced by concanavalin A in a dose dependent manner (50% inhibition at