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Selective impairment of gene expression and assembly of nephrin in human diabetic nephropathy

✍ Scribed by Benigni, Ariela; Gagliardini, Elena; Tomasoni, Susanna; Abbate, Mauro; Ruggenenti, Piero; Kalluri, Raghu; Remuzzi, Giuseppe

Book ID
109065483
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
407 KB
Volume
65
Category
Article
ISSN
0085-2538

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## Abstract CDK9 associates with T‐type cyclins and positively regulates transcriptional elongation by phosphorylating RNA polymerase II (RNAPII) and negative elongation factors. However, it is unclear whether CDK9 is required for transcription of most genes by RNAPII or alternatively plays a role