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Selective identification of HLA-DP4 binding T cell epitopes encoded by the MAGE-A gene family

✍ Scribed by Xiao-Fei Wang; William M. Cohen; Florence A. Castelli; Christine Almunia; Bernard Lethé; Sandra Pouvelle-Moratille; Gaetan Munier; Dominique Charron; André Ménez; Hassan M. Zarour; Pierre van der Bruggen; Marc Busson; Bernard Maillère

Publisher: Springer-Verlag
Year: 2006
Tongue: English
Weight: 704 KB
Volume: 56
Category: Article
ISSN: 0340-7004
DOI: 10.1007/s00262-006-0230-y

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## MAGE -2 is expressed in many tumors, including melanoma, laryngeal tumors, lung tumors and sarcomas, but not in healthy tissue, with the exception of testis. Thus, MAGE-2derived peptides that bind to HLA class I molecules and elicit cytotoxic T lymphocyte (CTL) responses could be of significant