Conjugate reduction of polyfunctional ฮฑ,
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Thomas M. Koenig; John F. Daeuble; Donna M. Brestensky; Jeffrey M. Stryker
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Article
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1990
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Elsevier Science
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French
โ 301 KB
In contrast to organocuprate conjugate addition and standard methods for conjugate reduction, use of the stable copper0 hydride cluster, [(ph3p)cuH)6, allows chemoselective conjugate reduction of o&msaturated carbonyl compounds substituted at the ~position with leaving groups. In addition, the compa