## Abstract Chlorozinc enolates of (hetero)aryl‐, alkyl‐ and silyl‐substituted acetates were reacted with imines and α‐diimines. The zinc‐mediated reaction of (hetero)aryl‐substituted acetates with imines afforded __trans__‐β‐lactams in good yields and with excellent selectivity. Zinc enolates of n
Selective formation of 1,3,4-trisubstituted and 3,4-disubstituted trans-β-lactams from zinc enolates and imines
✍ Scribed by Johann T. B. H. Jastrzebski; Fred H. van der Steen; Gerard van Koten
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 291 KB
- Volume
- 106
- Category
- Article
- ISSN
- 0165-0513
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📜 SIMILAR VOLUMES
A new one-pot synthesis of 3-amino-g-lactams that is based on the condensation of simple imines with zinc enolates of disilyl protected glycine esters is mported Isolated yields are high and a rranr-selectivity is observed. ## with imines. With N-(benzylidene)-trimethylsilylamine the ring-closure
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
## Abstract 2‐Chloro‐4‐phenyl‐2a‐(4′‐methoxyphenyl)‐3,5‐dihydroazatetracyclic [1,2‐__d__]benzo [ 1,4]diazepin‐1 ‐one (**III**~a~) and 2‐chloro‐4‐methyl‐2a‐(4′‐methoxyphenyl)‐3,5‐dihydroazatetracyclic[1,2‐__d__]‐benzo[1,4]diazepin‐1‐one (**III**~b~) were synthesized. 1‐Benzoyl‐2‐phenyl‐4‐(4′‐methoxy