Selective expansion of t cells bearing the γ/δ receptor and expressing an unusual repertoire in the synovial membrane of patients with rheumatoid arthritis

Increased expression Of HLA—DQ antigens

Increased expression Of HLA—DQ antigens by interstitial cells and endothelium in the synovial membrane of rheumatoid arthritis patients compared with reactive arthritis patients

✍ Diana Barkley; Simon Allard; Marc Feldmann; Ravinder N. Maini 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 918 KB

We investigated cellular phenotypes and expression of class I1 major histocompatibility complex antigens on endothelium and cellular infiltrates in synovium from patients with rheumatoid arthritis (RA) or reactive arthritis, using an indirect immunoperoxidase technique. The RA specimens showed synov