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Selective expansion of genetically modified T cells using an antibody/interleukin-2 receptor chimera

✍ Scribed by Takahiro Sogo; Masahiro Kawahara; Kouhei Tsumoto; Izumi Kumagai; Hiroshi Ueda; Teruyuki Nagamune


Book ID
113717567
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
834 KB
Volume
337
Category
Article
ISSN
0022-1759

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## Abstract A variant of the Jurkat leukemia cell line termed JA3 (surface phenotype: T11 +, T3 +, T4‐, T8‐, T6‐, T1 +, 3A1 +, HLA‐DR‐, Tac‐, 4FZ+) has been used for mouse immunization and production of monoclonal antibodies (MAbs) to molecules carrying clonotypic determinants that are thought to s