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Selective enrichment of phosphopeptides by a metal–organic framework

✍ Scribed by Messner, Christoph B.; Mirza, Munazza R.; Rainer, Matthias; Lutz, Oliver M. D.; Güzel, Yüksel; Hofer, Thomas S.; Huck, Christian W.; Rode, Bernd M.; Bonn, Günther K.


Book ID
120193585
Publisher
The Royal Society of Chemistry
Year
2013
Tongue
English
Weight
315 KB
Volume
5
Category
Article
ISSN
1759-9660

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## Abstract The selective enrichment of phosphopeptides with good reproducibility is vital for the in‐depth study of the phosphoproteome. Herein, we presented a novel method to prepare monolithic Ti^4+^ or Zr^4+^ immobilized metal affinity chromatography (IMAC) columns. Since succinimide was of hig