Selection of high affinity ligands to he
โ
Kok Lian Ho; Khatijah Yusoff; Heng Fong Seow; Wen Siang Tan
๐
Article
๐
2002
๐
John Wiley and Sons
๐
English
โ 179 KB
M13 phages that display random disulfide constrained heptapeptides on their gpIII proteins were used to select for high affinity ligands to hepatitis B core antigen (HBcAg). Phages bearing the amino acid sequences C-WSFFSNI-C and C-WPFWGPW-C were isolated, and a binding assay in solution showed that