We successfully synthesized a novel peroxisome proliferator-activated receptor (PPAR)d selective agonist, namely, compound 20, with a characteristic benzisoxazole ring. Compound 20 exhibited potent human PPARd transactivation activity and high d selectivity. Further, it stimulated differentiation of
✦ LIBER ✦
Selective effects of PPARγ agonists and antagonists on human pre-adipocyte differentiation
✍ Scribed by C. Leyvraz; M. Suter; C. Verdumo; J.-M. Calmes; A. Paroz; C. Darimont; R. C. Gaillard; F. P. Pralong; V. Giusti
- Book ID
- 109044907
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 888 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1462-8902
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