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Selective differentiation of CD4+ T helper cell subsets

✍ Scribed by Phillip Scott

Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
919 KB
Volume
5
Category
Article
ISSN
0952-7915

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✦ Synopsis

During the past year significant advances have been made in our understanding of the factors contributing to the differentiation of CD4 T helper cell subsets. These have been driven, in part, by the realization that signals (cytokines) from the innate immune response are critical in T cell subset differentiation. In addition, several studies have also elucidated how the antigen-presenting cell, the antigenic epitope and the antigen concentration may contribute to the selective development of a particular T helper cell subset.

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