Selective determination of organofluorine compounds by capillary column gas chromatography with an atmospheric pressure helium microwave-induced plasma detector
✍ Scribed by Brill, J. H. ;Narayanan, B. A. ;Doom, J. P. ;McCormick, J. P.
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 550 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0935-6304
No coin nor oath required. For personal study only.
✦ Synopsis
Fluorinated analogs of compounds typical of those found in metabolic and other biological studies are detected with high selectivity using a gas chromatograph/microwave-induced plasma detector (GC-MIPD), which permits fluorine-selective detection by monitoring the emission at 685.6 nm. Using the described atmospheric pressure helium-sustained plasma detector, the minimum detectable level, fluorine selectivity (relative to carbon), and linear dynamic range of this GC-MIPD system were determined to be 4.8 pg-F/s, 1060, and 5000, respectively. Theutilityof thisGC-MIPDsystemfortheselective detection of organofluorine compounds is demonstrated by its application in the analysis of the metabolic fate of a fluorinated substrateadministered to amixtureof wheat germ phosphatase and potato apyrase, as well as by analysis of synthetic mixtures.