Selective Degradation of the PKC-ϵ Isoform during Cell Death in AKR-2B Fibroblasts

Platelet-derived growth factor isoforms

Platelet-derived growth factor isoforms prevent cell death during starvation of AKR-2B fibroblasts

✍ Andreas Simm; Viviane Hoppe; Jürgen Hoppe; Aviv Gazit 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 862 KB

Confluent AKR-2B fibroblasts rapidly desintegrate upon removal of serum until a final density of -50% of the initial value was reached after 12 h. This density remained unchanged for at least 48 h. Platelet-derived growth factor (PDGF)-BB stimulated more than 95% of these cells to divide. PDGF-AB or