## Abstract Enkephalin is reported to play an important role in the pathophysiology of levodopa (LD) ‐induced dyskinesias. The present study investigated the effect of chronic treatment with a selective NR1A/2B __N__‐methyl‐D‐aspartate (NMDA) receptor antagonist, CI‐1041, on the expression of prepr
Selective D2 receptor stimulation induces dyskinesia in parkinsonian monkeys
✍ Scribed by M. Rosario Luquin; Janeth Laguna; Dr Jose A. Obeso
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 398 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Certain aminotetralins are known to be potent dopamine D~2~ receptor agonists. N‐0923, [‐]2‐(N‐propyl‐N‐2‐thienylethylamino)‐5‐hydroxytetralin HCl, recognizes the high and low affinity states of the D~2~ receptor in membranes from bovine caudate with a K~low~ of 79 nM. The selectivity r
The neuroanatomical and functional relationships between dopamine (DA) and neurotensin (NT) and DA and neuropeptide Y (NPY) suggest a role for these neuropeptides in DA-related neuropsychiatric disorders. By employing a microdialysis technique in conjunction with radioimmunoassay (RIA), the effects
Positron emission tomography was used to examine the in vivo binding of [ 11 C]raclopride to D 2 -dopamine (DA) receptors in the striatum of two Cynomolgus monkeys after a single dose of reserpine (1 mg/kg, i.v.). A Scatchard procedure was repeated five times to follow D 2 receptor density and appar