Glycine-selective Ξ±-carbon-nitrogen bond
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Christopher J. Easton; Sharon K. Eichinger; Michael J. Pitt
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Article
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1997
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Elsevier Science
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French
β 456 KB
Nickel peroxide selectively cleaves the s-carbon-nitrogen bond of glycine residues in dipeptide derivatives to give the corresponding amides, The glycine selectivity is attributable to preferential complexation of the reactant residue to nickel peroxide and subsequent reaction via a stable o~-centre