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Selective Cleavage of C-Tryptophyl Peptide Bonds in Proteins and Peptides

✍ Scribed by Ramachandran, L. K.; Witkop, B.


Book ID
127359288
Publisher
American Chemical Society
Year
1959
Tongue
English
Weight
585 KB
Volume
81
Category
Article
ISSN
0002-7863

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The chemical cleavage of amide (peptide) bonds usually requires harsh conditions. [1] As a result, side reactions and the lack of specificity of chemical amide-bond hydrolysis limits its scope in chemical biology and synthetic applications. Herein, we disclose our results on the selective cleavage o