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Selective Blockade of Vascular Endothelial Growth Factor Receptor 2 With an Antibody Against Tumor-Derived Vascular Endothelial Growth Factor Controls the Growth of Human Pancreatic Adenocarcinoma Xenografts

✍ Scribed by Shane E. Holloway; Adam W. Beck; Latha Shivakumar; Jessica Shih; Jason B. Fleming; Rolf A. Brekken


Book ID
111771624
Publisher
Springer
Year
2006
Tongue
English
Weight
428 KB
Volume
13
Category
Article
ISSN
1068-9265

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✍ Christiane J. Bruns; Marissa Shrader; Matthew T. Harbison; Charles Portera; Carm πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 French βš– 768 KB

## Abstract Vascular endothelial growth factor (VEGF) is the major pro‐angiogenic factor for most tumors. VEGF expression has been shown to be associated with a poor prognosis in human pancreatic cancer. The purpose of our study was to determine the effect of blockade of VEGF receptor‐2 activity wi