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Selective Blockade of Type-1 Metabotropic Glutamate Receptors Induces Neuroprotection by Enhancing Gabaergic Transmission

✍ Scribed by Giuseppe Battaglia; Valeria Bruno; Antonio Pisani; Diego Centonze; Maria Vincenza Catania; Paolo Calabresi; Ferdinando Nicoletti


Book ID
115637759
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
803 KB
Volume
17
Category
Article
ISSN
1044-7431

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Selective blockade of mGlu5 metabotropic
✍ Cristiano R. Jesse; Ethel A. Wilhelm; Cristiani F. Bortolatto; Lucielli Savegnag πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 432 KB

## Abstract This study was designed to investigate the influence of 2‐methyl‐6‐phenylethynyl pyridine hydrochloride (MPEP), an antagonist of metabotropic glutamate receptor subtype 5, in lipopolysaccharide (LPS) and d‐galactosamine (d‐GalN)‐induced fulminant hepatic failure in mice. Mice were given