𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Selective blockade of mGlu5 metabotropic glutamate receptors is protective against acetaminophen hepatotoxicity in mice

✍ Scribed by Marianna Storto; Richard Teke Ngomba; Giuseppe Battaglia; Isabel Freitas; Patrizia Griffini; Plinio Richelmi; Ferdinando Nicoletti; Mariapia Vairetti

Book ID
118564865
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
575 KB
Volume
38
Category
Article
ISSN
0168-8278

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Selective blockade of mGlu5 metabotropic
Selective blockade of mGlu5 metabotropic glutamate receptors protects rat hepatocytes against hypoxic damage
✍ Marianna Storto; Ugo de Grazia; Thomas Knöpfel; Pier Luigi Canonico; Agata Copan 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 367 KB

Western blot analysis of protein extracts from rat liver revealed the presence of the mGlu5 receptor, one of the G-protein-coupled receptors activated by glutamate (named ''metabotropic glutamate receptors'' or mGlu receptors). mGlu5 expression was particularly high in extracts from isolated hepatoc

Selective blockade of mGlu5 metabotropic
Selective blockade of mGlu5 metabotropic glutamate receptors is hepatoprotective against fulminant hepatic failure induced by lipopolysaccharide and d-galactosamine in mice
✍ Cristiano R. Jesse; Ethel A. Wilhelm; Cristiani F. Bortolatto; Lucielli Savegnag 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 432 KB

## Abstract This study was designed to investigate the influence of 2‐methyl‐6‐phenylethynyl pyridine hydrochloride (MPEP), an antagonist of metabotropic glutamate receptor subtype 5, in lipopolysaccharide (LPS) and d‐galactosamine (d‐GalN)‐induced fulminant hepatic failure in mice. Mice were given