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Selective and efficient inhibition of the alternative pathway of complement by a mAb that recognizes C3b/iC3b

โœ Scribed by David J. DiLillo; Andrew W. Pawluczkowycz; Wu Peng; Adam D. Kennedy; Paul V. Beum; Margaret A. Lindorfer; Ronald P. Taylor


Book ID
116755624
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
511 KB
Volume
43
Category
Article
ISSN
0161-5890

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A mechanism of activation of the alterna
โœ Seppo Meri; Michael K. Pangburn ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 716 KB

## A mechanism of activation of the alternative complement pathway by the classical pathway: protection of C3b from inactivation by covalent attachment to C4b* In this work we studied the role of the classical pathway complement component C4b in the activation of the alternative pathway. It was fo