## Abstract Previous studies have demonstrated that both mechanical perturbation and cell adhesion induced the expression of osteopontin (__opn)__ by osteoblasts (Carvalho et al. [1998] J. Cell. Biochem. 70:376β390). The present study examined if these same stimuli on osteoblasts would induce the e
Selective adhesion of osteoblastic cells to different integrin ligands induces osteopontin gene expression
β Scribed by R.S. Carvalho; P.J. Kostenuik; E. Salih; A. Bumann; L.C. Gerstenfeld
- Book ID
- 117640309
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 511 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0945-053X
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Osteopontin is a predominant integrin binding protein of bone and its expression has been shown to be induced by mechanical stimuli within osteoblasts J. Bone Miner. Res. 12:1626Res. 12: -1636)). The present studies examined if the cell adhesion would mimic the mechano-transduction that stimulated
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