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Selective activation of NF-κB subunits in human breast cancer: potential roles for NF-κB2/p52 and for Bcl-3

✍ Scribed by Cogswell, Patricia C; Guttridge, Denis C; Funkhouser, William K; Baldwin, Albert S


Book ID
110062758
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
518 KB
Volume
19
Category
Article
ISSN
0950-9232

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✍ Alfredo Ricca; Annamaria Biroccio; Donatella Del Bufalo; Andrew R. Mackay; Angel 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 204 KB 👁 1 views

bcl-2 expression is often associated with poor prognosis in several types of tumors; however, the role of this molecule in breast cancer is still controversial. We found earlier that over-expression of bcl-2 in a human breast-cancer cell line (MCF7 ADR ) enhances its tumorigenicity and metastatic po