Selective ablation of bone marrow-derived dendritic cells increases amyloid plaques in a mouse Alzheimer's disease model
✍ Scribed by Oleg Butovsky; Gilad Kunis; Maya Koronyo-Hamaoui; Michal Schwartz
- Book ID
- 109026043
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 766 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0953-816X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Bone marrow (BM)‐derived monocytes contribute to the development of microglial reaction around β‐amyloid (Aβ) plaques in Alzheimer's disease (AD) and possibly clear Aβ. Therefore, it is of great importance to separate the proinflammatory actions of monocytic cells from Aβ phagocytic eff
## Abstract Parkinson's disease (PD) is a neurodegenerative disease characterized by progressive degeneration of nigrostriatal dopaminergic (DA) neurons. The therapeutic potential of glial cell line‐derived neurotrophic factor (GDNF), the most potent neurotrophic factor for DA neurons, has been dem