Selection response for litter size at birth and litter weight at weaning in the first parity in mice
✍ Scribed by B. G. Luxford; R. G. Beilharz
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 662 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0040-5752
No coin nor oath required. For personal study only.
✦ Synopsis
Five 60-pair lines of mice were selected for seven generations for the following criteria: number born alive (LSO), random selection of litters (LC), number born alive divided by the weight of the dam at 9 weeks (LSO/DWT), total litter weight weaned divided by the weight of the dam at 9 weeks (LWT/DWT), and weight of litter weaned (LWT). All traits were measured in the first parity only and litters were not standardized. Realized heritabilities for LSO, LWT, LSO/DWT, and LWT/ DWT were 0.10± 0.06, 0.11±0.07, 0.22 ± 0.04, and 0.22 ± 0.08, respectively. Selection response for the two ratio lines was due to correlated responses in the respective numerators, LSO and LWT, as DWT did not decrease. In terms of improving LWT, selection for LWT/ DWT was three times as effective as selection for LSO/ DWT.
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## Abstract The mechanism whereby poor intrauterine growth increases risk of adult hip fracture is unclear. We report the association between birth weight and proximal femoral geometry and density in community‐dwelling elderly men. We used self‐reported birth weight, measured adult height and weigh