The ontogeny of interleukin 2 (IL2) production in young CBAIHT6T6.l mice was studied using both bulk culture and limiting dilution methods. The ability of spleen cells in bulk culture to produce IL2 in response to concanavalin A (Con A) was found to rise through the first 2 weeks of life, from no pr
β¦ LIBER β¦
Selection of the T cell repertoire during ontogeny: Limiting dilution analysis
β Scribed by Hung-Sia Teh; Jack Bennink; Harald von Boehmer
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 592 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0014-2980
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## Abstract The longβterm stability of renal grafts depends on the absence of chronic rejection. As T cells play a key role in rejection processes, analyzing the Tβcell repertoire may be useful for understanding graft function outcomes. We have therefore investigated the power of a new statistical