✦ LIBER ✦

Selection of optimal dose

✍ Scribed by M.K. Khan; M.A. Khan

Publisher: Elsevier Science
Year: 1985
Tongue: English
Weight: 640 KB
Volume: 18
Category: Article
ISSN: 0010-4809
DOI: 10.1016/0010-4809(85)90045-x

No coin nor oath required. For personal study only.

✦ Synopsis

Dose and dilution levels for quantal response bioassays and dilution assays are selected rather arbitrary. Some guidelines for designing experiments for binary data arising in such fields as bioassay studies, dilution series assays, and dose-response curves are provided. It is shown that for estimation purposes, the study should be designed in such a way so that the experimental doses lie around a critical interval. Failure to do so many produce serious bias in the Maximum Likelihood estimates. This critical interval, however, depends on the unknown parameters. With the help of extensive computer simulations for the logit model ways of overcoming this difficulty are outlined.

📜 SIMILAR VOLUMES

Optimal selection of forecasts

✍ Lian Chen; G. Anandalingam 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 732 KB

Many studies have shown that, in general, a combination of forecasts often outperforms the forecasts of a single model or expert. In this paper we postulate that obtaining forecasts is costly, and provide models for optimally selecting them. Based on normality assumptions, we derive a dynamic progra

Optimal selection of IC fabrication para

Optimal selection of IC fabrication parameters

✍ C. Karmokolias; W. M. Portnoy; R. E. Saeks 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 282 KB

Optimal adaptive selection of sampling s

Optimal adaptive selection of sampling sites

✍ Chang-Tai Chao; Steven K. Thompson 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 436 KB

Selection of the optimal setup policy

✍ Shaul P. Ladany; Dina N. Bedi 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 English ⚖ 758 KB

Selection of optimal VOC-condensation sy

Selection of optimal VOC-condensation systems

✍ Russell F. Dunn; Mahmoud M. El-Halwagi 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 732 KB

Optimal slope selection via expanders

✍ Matthew J. Katz; Micha Sharir 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 532 KB