## Abstract Lamivudine results in the selection of resistant hepatitis B virus (HBV) variants. Because the surface gene of HBV overlaps completely the polymerase gene, the incidence and profile of surface and polymerase gene mutations were investigated prospectively in chronic HBV patients who were
Selection of mutations in the hepatitis B virus polymerase during therapy of transplant recipients with lamivudine
β Scribed by R Ling; D Mutimer; M Ahmed; E H Boxall; E Elias; G M Dusheiko; T J Harrison
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 180 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0270-9139
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## Abstract Recurrent hepatitis B virus (HBV) infection after liver transplantation can be prevented by prophylactic hepatitis B immune globulin (HBIG) and lamivudine therapy. However, reinfection may still occur due to the emergence of immune escape mutants and mutants of the YMDD motif. The full
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