Contributions to Group 17 of the Genetic Analysis Workshop 15 considered dense markers in linkage disequilibrium (LD) in the context of either linkage or association analysis. Three contributions reported on methods for modeling LD or selecting a subset of markers in linkage equilibrium to perform l
โฆ LIBER โฆ
Selection of Genetic Markers for Association Analyses, Using Linkage Disequilibrium and Haplotypes
โ Scribed by Zhaoling Meng; Dmitri V. Zaykin; Chun-Fang Xu; Michael Wagner; Margaret G. Ehm
- Book ID
- 117854252
- Publisher
- American Society of Human Genetics
- Year
- 2003
- Tongue
- English
- Weight
- 488 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0002-9297
- DOI
- 10.1086/376561
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## Abstract Association studies depend on linkage disequilibrium (LD) between a causative mutation and linked marker loci. Selecting markers that give the best chance of showing useful levels of LD with the causative mutation will increase the chances of successfully detecting an association. This