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Selection of candidates with HCC for transplantation in the MELD era

✍ Scribed by Margarita Sala; Maria Varela; Jordi Bruix


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
80 KB
Volume
10
Category
Article
ISSN
1527-6465

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✦ Synopsis


Key Points

  1. Liver transplantation is the main option for patients with early HCC who are not optimal candidates for surgical resection. 2. Shortage of donors is its main limitation, as waiting for a liver allows the tumor to progress and induce exclusion from the waiting list and death. 3. The absence of randomized controlled trials hinders the establishment of the most effective therapy to prevent tumor progression while waiting. 4. Live donation may be a cost-effective approach if optimal results are expected and the mortality risk for the donor is kept below .3%. 5. Priority policies have to be developed and refined to provide a fair and effective distribution of cadaveric organs. (Liver Transpl 2004;10:

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