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Selection for carriers of recessive diseases: A common phenomenon?

✍ Scribed by Zlotogora, Jo�l

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
6 KB
Volume
80
Category
Article
ISSN
0148-7299

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✦ Synopsis

Several autosomal recessive disorders are present in high frequency in isolated populations because of either multiple allelic mutations or mutations in different genes. These observations are best explained by selection, which may be an important mechanism in the determination of the distribution of genetic disorders.

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