The humoral immune response of camels, dromedaries and llamas includes functional antibodies formed by two heavy chains and no light chains. The amino acid sequence of the variable domain of the naturally occurring heavy-chain antibodies reveals the necessary adaptations to compensate for the absenc
β¦ LIBER β¦
Selection and identification of single domain antibody fragments from camel heavy-chain antibodies
β Scribed by M Arbabi Ghahroudi; A Desmyter; L Wyns; R Hamers; S Muyldermans
- Book ID
- 117108159
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 771 KB
- Volume
- 414
- Category
- Article
- ISSN
- 0014-5793
No coin nor oath required. For personal study only.
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## Abstract The variable domain of functional heavy chain antibodies (VHH) devoid of light chains, found in camels, constitute the smallest intact antigenβbinding domain fragment. Two camel singleβdomain fragments, cAbβLys2 and cAbβLys3, recognizing an overlapping epitope of lysozyme with a dissoci
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