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Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured fab in complex with antigen

โœ Scribed by Yvonne Chen; Christian Wiesmann; Germaine Fuh; Bing Li; Hans W Christinger; Patrick McKay; Abraham M de Vos; Henry B Lowman


Book ID
115629717
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
371 KB
Volume
293
Category
Article
ISSN
0022-2836

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Structure of an anti-cholera toxin antib
โœ Patrick Scheerer; Achim Kramer; Livia Otte; Martina Seifert; Helga Wessner; Chri ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 473 KB

## Abstract The structure of a complex of the antiโ€cholera toxin antibody TE33 Fab (fragment antibody) with the Dโ€peptide **vpGsqhyds** was solved to 1.78โ€‰ร… resolution. The Dโ€peptide was derived from the linear Lโ€peptide epitope VPGSQHIDS by a stepwise transformation. Despite the very similar amino