SELDI-TOF-MS profiling of serum for early detection of colorectal cancer
β Scribed by Drake, Richard R.; Manne, Upender; Adam, Bao-Ling; Ahn, Christina; Cazares, Lisa; Semmes, O.J.; Bigbee, William L.; Grizzle, William E.; Johnson, David A.
- Book ID
- 122176995
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 235 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0016-5085
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Proteomic profiling of serum is an emerging technique to identify new biomarkers indicative of disease severity and progression. The objective of our study was to assess the use of surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) to identify multiple serum
## Background Many highβabundant acute phase reactants have been previously detected as potential breast cancer biomarβkers. However, they are unlikely to be specific for breast cancer. Cancerβspecific biomarkers are thought to be among the lower abundant proteins. ## Methods We aimed to detect l