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Seizure-mediated neuronal activation induces DREAM gene expression in the mouse brain

✍ Scribed by Toru Matsu-ura; Yoshiyuki Konishi; Tsutomu Aoki; Jose R Naranjo; Katsuhiko Mikoshiba; Taka-aki Tamura

Book ID
117386079
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
605 KB
Volume
109
Category
Article
ISSN
0169-328X

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## Abstract To achieve inducible and reversible gene expression in the adult mouse brain, we exploited an improved version of the tetracycline‐controlled transactivator‐based system (rtTA2^S^‐M2, rtTA2 hereafter) and combined it with the forebrain‐specific CaMKIIα promoter. Several independent line