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Seizing the Opportunity: Recognition and Management of Hereditary Cancer Predisposition

โœ Scribed by Mark E. Robson


Book ID
114474092
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
61 KB
Volume
34
Category
Article
ISSN
0093-7754

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โœ Edelmann, Lisa ;Edelmann, Winfried ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 143 KB ๐Ÿ‘ 2 views

## Abstract Germline mutations in DNA mismatch repair genes underlie one of the most common hereditary cancer predisposition syndromes known in humans, hereditary nonpolyposis colorectal cancer (HNPCC). Defects of the DNA mismatch repair system are also prevalent in sporadic colorectal cancers. The