Segregation analysis of HDL cholesterol in the NHLBI Family Heart Study and in Utah pedigrees
โ Scribed by Kronenberg, Florian; Coon, Hilary; Ellison, R Curtis; Borecki, Ingrid; Arnett, Donna K; Province, Michael A; Eckfeldt, John H; Hopkins, Paul N; Hunt, Steven C
- Book ID
- 110025239
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 110 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1018-4813
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
We perfom both segregation and linkage analysis for an hypothesized breast cmxr suscqt&ility gene u d e r a s w l e analyze these families, we present a breast cancer penetrance model a sirrgle parameter for each gemtype. lmis is in corrtrast to previms models that require two or more parameters for
FHxS is related to total cholesterol and HDLc but also is an independent predictor of subsequent ischemic heart disease after 14-18 years of follow-up.
Robust methods were employed, using data from a single large pedigree, to screen serum apolipoprotein A1 and B levels, serum lipoprotein cholesterol levels, and ratios of serum lipoprotein cholesterol fractions to apolipoprotein A1 and B levels for genetic linkage to 31 polymorphic markers. Segregat