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Segregation analysis of balanced pericentric inversions in pedigree data

✍ Scribed by S. L. Sherman; L. Iselius; P. Gallano; K. Buckton; S. Collyer; R. DeMey; U. Kristoffersson; J. Lindsten; M. Mikkelsen; N. E. Morton; M. Newton; I. Nordensson; M. B. Petersen; J. Wahlström


Book ID
115089395
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
475 KB
Volume
30
Category
Article
ISSN
0009-9163

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Little is known about the cause of hypospadias, one of the most common urogenital anomalies in males. Familial clustering of hypospadias is well recognized, with heritability estimated to be about 70%under a simple multifactorial threshold model. Neither alternative genetic mechanisms nor shared env