## Abstract We have conducted a segregation analysis in order to characterise the transmission of Behรงet Disease (BD), a multifactorial condition with a strong genetic component. Complete information about BD status and pedigree was obtained on 104 probands from our database. We used the criteria o
Segregation analysis of 1,546 prostate cancer families in Finland shows recessive inheritance
โ Scribed by Sanna Pakkanen; Agnes B. Baffoe-Bonnie; Mika P. Matikainen; Pasi A. Koivisto; Teuvo L. J. Tammela; Snehal Deshmukh; Liang Ou; Joan E. Bailey-Wilson; Johanna Schleutker
- Book ID
- 106134498
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 230 KB
- Volume
- 121
- Category
- Article
- ISSN
- 0340-6717
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Reports on the prognosis of familial breast cancer patients have been contradictory. True differences in survival, if they exist, would have important implications for genetic counselling and in treatment of hereditary breast cancer. We assessed the survival rates of 359 familial breast cancer patie
An estimated 5โ10% of all breast and ovarian cancers are due to an inherited predisposition, representing a rather large number of patients. In Spain 1/13โ1/14 women will be diagnosed with breast cancer during their lifetime. Two major breast cancer genes, __BRCA1__ and __BRCA2__, have been identifi