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Segregation analysis in hereditary retinoblastoma

✍ Scribed by Catherine Bonaïti-Pellié; Marie Louise Briard-Guillemot

Book ID
104702641
Publisher
Springer
Year
1981
Tongue
English
Weight
583 KB
Volume
57
Category
Article
ISSN
0340-6717

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Segregation analysis of eleven families comprising 2762 individuals indicated compatibility of the data with segregation of a major autosomal dominant gene for hereditary nonpolyposis colorectal cancer. It was estimated that between 71% and 79% of the gene carriers were susceptible and had age of on