Segmental expression of the T-box transcription factor, Tbx2, during early somitogenesis
β Scribed by Zachary Harrelson; Virginia E. Papaioannou
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 662 KB
- Volume
- 235
- Category
- Article
- ISSN
- 1058-8388
No coin nor oath required. For personal study only.
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## Abstract Tbx2 is a member of the Tβbox family of transcription factors that are crucial in embryonic development. Recent studies suggest that Tβbox factors may also play a role in controlling cell cycle progression and in the genesis of cancer. Tbx2 has been implicated in several developmental p
## Abstract The Tβbox transcription factor, __Tbx1__, an important regulatory gene in development, is highly expressed in hair follicle (HF) stem cells in adult mice. Because mouse models of skin carcinogenesis have demonstrated that HF stem cells are a carcinogen target population and contribute s